897364-70-4Relevant academic research and scientific papers
2-position base-modified analogues of adenophostin A as high-affinity agonists of the D-myo-inositol trisphosphate receptor: In vitro evaluation and molecular modeling
Sureshan, Kana M.,Trusselle, Melanie,Tovey, Stephen C.,Taylor, Colin W.,Potter, Barry V. L.
, p. 1682 - 1692 (2008/09/20)
(Figure Presented) Adenophostin A (AdA) is a potent agonist of the D-myo-inositol 1,4,5-trisphosphate receptor (Ins(1,4,5)P3R). Various 2-aminopurine analogues of AdA were synthesized, all of which (guanophostin 5, 2,6-diaminopurinophostin 6, 2
Guanophostin A: Synthesis and evaluation of a high affinity agonist of the D-myo-inositol 1,4,5-trisphosphate receptor
Sureshan, Kana M.,Trusselle, Melanie,Tovey, Stephen C.,Taylor, Colin W.,Potter, Barry V. L.
, p. 2015 - 2017 (2008/09/18)
Guanophostin A, the guanosine counterpart of the inositol 1,4,5-trisphosphate receptor agonist adenophostin A, has been synthesized and is the first synthetic adenophostin A-like analogue to be equipotent to its parent in stimulating intracellular Ca
