897380-80-2

Upstream product

• 773-64-8 2-mesitylenesulphonyl chloride 
• 764629-04-1 2-amino-3,3,3-trifluoropropionic acid ethyl ester 

Downstream Products

• 897380-81-3 2,4,6-trimethyl-N-(2,2,2-trifluoro-1-hydroxymethylethyl)benzenesulfonamide 
• 1070749-90-4 2,4,6-trimethyl-N-(2,2,2-trifluoro-1-phenylaminomethylethyl)benzene-sulfonamide 
• 1070749-82-4 2,4,6-trimethyl-N-(2,2,2-trifluoro-1-phenoxymethylethyl)-benzenesulfonamide 
• 1070749-80-2 2,4,6-trimethyl-N-(2,2,2-trifluoro-1-phenylsulfanylmethylethyl)benzene-sulfonamide 
• 897380-82-4 1-(2,4,6-trimethylbenzenesulfonyl)-2-(trifluoromethyl)aziridine 

Relevant academic research and scientific papers

GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF

Compounds of Formula (I) wherein R1, R2, R3, R4, R5, R6, X, R7, and R8 are as defined herein, or a tautomer, prodrug, solvate, or salt thereof; pharmaceutical compositions containing such compounds, and methods of modulating the glucocorticoid receptor function and methods of treating disease-states or conditions mediated by the glucocorticoid receptor function or characterized by inflammatory, allergic, or proliferative processes in a patient using these compounds.