897397-74-9Relevant academic research and scientific papers
Catalysis and regioselectivity of the aqueous Heck reaction by Pd(0) nanoparticles under ultrasonic irradiation
Zhang, Zuhui,Zha, Zhenggen,Gan, Changsheng,Pan, Chongfeng,Zhou, Yuqing,Wang, Zhiyong,Zhou, Ming-Ming
, p. 4339 - 4342 (2007/10/03)
An aqueous Heck reaction carried out under ultrasonic irradiation at the ambient temperature (25 °C) has been shown in this study to afford high yields of corresponding products. It was found that as a catalyst for the reaction palladium forms nanoparticles in-situ, characterized by transmission electron microscopy (TEM) and X-ray powder diffraction (XRD) analyses, and can be recycled. Furthermore, the Heck reaction under such mild and environmentally friendly conditions offers excellent regioselectivity of para-over ortho-substitution in phenyl iodides especially with electron-donating groups.
