897407-09-9

Upstream product

• 94662-67-6 (E)-1-Benzylamino-1-(methylthio)-2-nitroethylene 
• 90-02-8 salicylaldehyde 

Downstream Products

• 1338924-91-6 2-[2-(benzylamino)-3-nitro-4H-4-chromenyl]-4-methylphenol 
• 1338924-92-7 2-[2-(benzylamino)-3-nitro-4H-4-chromenyl]-4-chlorophenol 

Relevant academic research and scientific papers

Nitroketene acetal chemistry: efficient synthesis of 2-amino-3-nitro-4H-chromenes

Base-catalyzed reaction of the nitroketene N,S-acetals and the ring substituted 2-hydroxybenzaldehydes afforded a combinatorial library of the 2-alkylamino-3-nitro-4-alkylsulfanyl 4H-chromenes in excellent yields. Nucleophilic displacement of the C4 alkylsulfanyl group with different thiols afforded 4H-chromenes with structural diversity.