89747-25-1Relevant academic research and scientific papers
Inhibition of Arabinose 5-Phosphate Isomerase. An Approach to the Inhibition of Bacterial Lipopolysaccharide Biosynthesis
Bigham, Eric C.,Gragg, Charles E.,Hall, William R.,Kelsey, John E.,Mallory, William R.,et al.
, p. 717 - 726 (2007/10/02)
Arabinose 5-phosphate (A5P) isomerase is a key enzyme in the biosynthesis of liposaccharide, an essential component of the outer membrane of Gram-negative bacteria.The mechanism of the isomerase is envisioned to involve an enediol intermediate.A series of
