897627-79-1Relevant academic research and scientific papers
Cd(NO3)2.4H2O catalyzed one-pot synthesis of 1,4-dihydropyridine and polyhydroquinoline derivatives through the Hantzsch multicomponent condensation
Tafer, Radia,Boulcina, Raouf,Carboni, Bertrand,Debache, Abdelmadjid
, p. 1555 - 1560 (2012)
The synthesis of various 1,4-dihydropyridine and polyhydroquinoline derivatives was achieved in good to excellent yields using cadmium (II) nitrate as catalyst to promote the classical andmodified Hantzsch conditions in good yields under mild conditions.
Synthesis of some new 1,4-dihydropyridine derivatives through a facile one-pot Hantzsch condensation catalyzed by triethylamine
Ghalem, Wassima,Boulcina, Raouf,Debache, Abdelmadjid
experimental part, p. 733 - 737 (2012/05/20)
A facile and efficient synthesis of new 1,4-dihydropyridine derivatives was reported via Hantzsch three-component condensation reaction of aldehydes or formylphenylboronic acids, ethyl acetoacetate, and ammonium acetate in the presence of a catalytic amount of triethylamine under solvent-free conditions. The method described here offers several advantages including high yields, short reaction times, and simple work-up procedure.
An efficient one-step synthesis of 1,4-dihydropyridines via a triphenylphosphine-catalyzed three-component Hantzsch reaction under mild conditions
Debache, Abdelmadjid,Ghalem, Wassima,Boulcina, Raouf,Belfaitah, Ali,Rhouati, Salah,Carboni, Bertrand
experimental part, p. 5248 - 5250 (2009/12/06)
An efficient one-step synthesis of 1,4-dihydropyridines in good to excellent yields via the triphenylphosphine-catalyzed Hantzsch three-component reaction of an aromatic aldehyde, ethyl acetoacetate and ammonium acetate is described.
One-pot synthesis of 1,4-dihydropyridines via a phenylboronic acid catalyzed Hantzsch three-component reaction
Debache, Abdelmadjid,Boulcina, Raouf,Belfaitah, Ali,Rhouati, Salah,Carboni, Bertrand
, p. 509 - 512 (2008/12/21)
A simple, inexpensive, and efficient one-pot synthesis of 1,4-dihydropyridine derivatives was achieved in good yields via the three-component reaction of aromatic aldehydes, ethyl acetoacetate, and ammonium acetate using PhB(OH)2 as catalyst. Georg Thieme Verlag Stuttgart.
COMPOUNDS AND COMBINATIONS THEREOF FOR INHIBITING BETA-AMYLOID PRODUCTION AND METHODS OF USE THEREOF
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Page/Page column 139, (2010/11/29)
Provided are compounds which can be used in combination for treating diseases associated with a condition associated with cerebral accumulation of Alzheimer’s amyloid, such as Alzheimer’s disease. Also provided are methods of treating or reducing the risk of developing β-amyloid production, β-amyloid deposition, β-amyloid neurotoxicity (including abnormal hyperphosphorylation of tau) and microgliosis associated with cerebral accumulation of Alzheimer’s amyloid by administering therapeutically effective amounts of compounds which in combination can decrease β-amyloid production and capacitative calcium entry in cells. Further provided are methods for diagnosing diseases associated with cerebral accumulation of Alzheimer’s amyloid in animals or humans by administering diagnostically effective amounts of the compounds.
