897918-40-0Relevant articles and documents
Efficient synthesis of achiral seco-cyclopropylbenz[2,3-e]indoline analogues: [4-Amino-2-(5,6,7-trimethoxyindole-2-carboxamido)naphthalen-1-yl] ethyl chloride and [4-hydroxy-2-(5,6,7-trimethoxyindole-2-carboxamido) naphthalen-1-yl]ethyl chloride
Sato, Atsushi,Scott, Adrienne,Asao, Tetsuji,Lee, Moses
, p. 4692 - 4695 (2006)
Achiral seco-aminocyclopropylbenz[2,3-e]indoline and seco- hydroxycyclopropylbenz[2,3-e]indoline (seco-CBI) analogues of the duocarmycins and CC-1065, e.g., 7 and 8, are potent anticancer agents. This paper describes significantly improved synthetic strat