898046-08-7

Upstream product

• 119-34-6 4-amino-2-nitrophenol 
• 27374-25-0 [(1-Ethoxycyclopropyl)oxy]trimethylsilane 

Downstream Products

• 897953-59-2 C₁₂H₁₆N₂O₅ 
• 897951-56-3 C₁₂H₁₄N₂O₅ 

Relevant academic research and scientific papers

Substituted Piperdines as Renin Inhibitors

The invention relates to substituted 3,4- or higher substituted piperididine compounds, the use thereof for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that cla

SUBSTITUTED PIPERIDINES AS RENIN INHIBITORS

The invention relates to substituted 3,4- or higher substituted piperididine compounds, the use thereof for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (= disorder) that depends on activity of renin; pharmaceutical formulations or products comprising said compounds, and/or a method of treatment comprising administering said compounds, a method for the manufacture of said compounds, as well as novel intermediates, starting materials and/or partial steps for their synthesis. The compounds preferably have the formula I, wherein the moieties R1, R2, R11 and W are as defined in the specification.