89806-12-2 Usage
Molecular Structure
It comprises a pyridine ring fused to a thiadiazole ring.
Functional Groups
Pyridine Ring: Present in the molecule.
Thiadiazole Ring: Contains a methylsulfonyl group (?SO2CH3) attached to the 5-position.
Nitrogen Oxide Group: Present in the molecule.
Potential Pharmaceutical Applications
Studied as a potential anticancer agent.
Biological Activity
Suggests potential interaction with biological molecules.
Interest in Medicinal Chemistry
It is considered an interesting target for further research in this field.
Pharmacological Properties
The presence of the nitrogen oxide group may contribute to its pharmacological effects.
Check Digit Verification of cas no
The CAS Registry Mumber 89806-12-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,8,0 and 6 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 89806-12:
(7*8)+(6*9)+(5*8)+(4*0)+(3*6)+(2*1)+(1*2)=172
172 % 10 = 2
So 89806-12-2 is a valid CAS Registry Number.
89806-12-2Relevant academic research and scientific papers
A New Approach for Convenient One-pot Synthesis of 5-(1-Oxidopyridyl)- and 5-(1-Oxidoquinolyl)-2-alkylsulphonyl-1,3,4-thiadiazoles
Kubota, Seiju,Toyooka, Kouhei,Misra, Hemant K.,Kawano, Michinobu,Shibuya, Masayuki
, p. 2957 - 2962 (2007/10/02)
Acetylation of pyridine-4-carbaldehyde methylthio(thiocarbonyl)hydrazone (1a) with acetic anhydride gave 4-acetyl-2-methylthio-5-(4-pyridyl)-4,5-dihydro-1,3,4-thiadiazole (2).Oxidation of compound (2) with 30percent hydrogen peroxide in acetic acid furnished 2-methylsulphonyl-5-(1-oxido-4-pyridyl)-1,3,4-thiadiazole (3a). 2-Alkylsulphonyl-1,3,4-thiadiazoles (3a-h) having 1-oxido-2-pyridyl, 1-oxido-3-pyridyl, 1-oxido-4-pyridyl, 1-oxido-2-quinolyl, and 1-oxido-4-quinolyl groups at the 5-position were obtained in good yields from the corresponding pyridine- (1a-f) and quinoline-carbaldehyde (1g) and (1h) alkylthio(thiocarbonyl)hydrazones by a one-pot synthesis.A reaction pathway from compound (2) to compound (3a) is also described.
