89808-77-5

Basic information

• Product Name: 5-(3-NITROPHENYL)-1,3-OXAZOLE
• Synonyms: 5-(3-NITROPHENYL)OXAZOLE;5-(3-NITROPHENYL)-1,3-OXAZOLE
• CAS NO: 89808-77-5
• Molecular Formula: C₉H₆N₂O₃
• Molecular Weight: 190.16
• Mol File: 89808-77-5.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 351.4 °C at 760 mmHg
• Flash Point: 166.3 °C
• Appearance: /
• Density: 1.333 g/cm³
• Vapor Pressure: 8.37E-05mmHg at 25°C
• Refractive Index: 1.584
• PKA: 0.06±0.10(Predicted)
• CAS DataBase Reference: 5-(3-NITROPHENYL)-1,3-OXAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(3-NITROPHENYL)-1,3-OXAZOLE(89808-77-5)
• EPA Substance Registry System: 5-(3-NITROPHENYL)-1,3-OXAZOLE(89808-77-5)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 89808-77-5(Hazardous Substances Data)

Usage

General Description

5-(3-Nitrophenyl)-1,3-oxazole is a chemical compound classified under the family of oxazoles. Oxazoles are organic compounds and heterocyclic aromatics that have a five-membered ring structure with two atoms being nitrogen and oxygen in the ring. It has a molecular weight of 213.15 and its systematic name is 5-(3-nitrophenyl)oxazole. Not much information is currently available regarding its properties or potential applications. Given the fact that it contains a nitrophenyl group, it may potentially be used as a precursor in organic synthesis or contribute to various chemical reactions. However, information about its usage, potential toxicity, environmental impact, or other factors is limited. Studies and evaluations would be necessary for a definitive understanding of its interactions and potential uses in various applications. It's important to handle it carefully wearing proper personal protective equipment as its health effects are unknown.

InChI:InChI=1/C9H6N2O3/c12-11(13)8-3-1-2-7(4-8)9-5-10-6-14-9/h1-6H

Upstream product

• 38622-91-2 [(p-methylphenyl)sulfonylmethyl]isonitrile 
• 99-61-6 3-nitro-benzaldehyde 

Downstream Products

• 157837-31-5 3-(5-oxazolyl)-benzenamine 

Relevant articles and documents

NOVEL OXAZOLE DERIVATIVES THAT INHIBIT SYK

The present invention is concerned with substituted oxazole derivatives that selectively modulate, regulate, and/or inhibit signal transduction mediated by certain native and/or mutant protein kinases implicated in a variety of human and animal diseases s

OXAZOLE AND THIAZOLE DERIVATIVES AS SELECTIVE PROTEIN KINASE INHIBITORS (C-KIT)

The present invention relates to compounds of formula I or pharmaceutically acceptable salts thereof: wherein R1, R2, R3, A, Q, W and X are as defined in the description. These compounds selectively modulate, regulate, and/or inhibit signal transduction mediated by certain native and/or mutant proteine kinases implicated in a variety of human and animal diseases such as cell proliferative, metabolic, allergic, and degenerative disorders. More particularly, these compounds are potent and selective native and/or mutant c-kit inhibitors.

HYDRAZONE DERIVATIVE

A compound represented by the following formula (I): wherein R1 represents hydrogen, aryl which may have a substituent, a saturated or unsaturated 5- to 7-membered heterocyclic group which may have a substituent, etc.; R2 represents hydrogen, aryl which may have a substituent, a saturated or unsaturated 5- to 7-membered heterocyclic group which may have a substituent, etc.; R3 represents hydrogen, etc.; Ar represents a divalent group derived from aromatic hydrocarbon, etc.; X represents a single bond, linear or branched alkylene having from 1 to 3 carbon atoms which may have a substituent, etc.; and G represents halogen, a saturated or unsaturated 5- or 6-membered cyclic hydrocarbon group which may have a substituent, a saturated or unsaturated 5- to 7-membered heterocyclic group which may have a substituent, etc., a salt thereof or a solvate thereof; and an agent for inhibiting aggregation and/or deposition of an amyloid protein or an amyloid-like protein, which comprises the compound, a salt thereof or a solvate thereof