89816-81-9

Basic information

• Product Name: 2,4-dimethylphenyl ethyl xanthate
• Synonyms: 2,4-dimethylphenyl ethyl xanthate
• CAS NO: 89816-81-9
• Molecular Weight: 226.364
• Mol File: 89816-81-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2,4-dimethylphenyl ethyl xanthate(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-dimethylphenyl ethyl xanthate(89816-81-9)
• EPA Substance Registry System: 2,4-dimethylphenyl ethyl xanthate(89816-81-9)

Safety Data

• Hazardous Substances Data: 89816-81-9(Hazardous Substances Data)

Upstream product

• 140-89-6 potassium ethyl xanthogenate 
• 95-68-1 2,4-Xylidine 

Downstream Products

• 13616-82-5 2,4-dimethyl-thiophenol 
• 1610527-49-5 2,4-dimethyl-1-[(2-nitro-phenyl)-sulfanyl]-benzene 
• 1019453-85-0 2-(2,4-dimethylphenylsulphanyl)benzeneamine 
• 89816-86-4 2-(2,4-dimethylphenylthio)cyclohexanone 
• 31317-18-7 2,4-dimethyldibenzo[b,d]thiophene 

Relevant articles and documents

Synthesis and biological evaluation of some bicyclic [2-(2,4-dimethylphenylthio)phenyl] aniline and its amide derivatives as potential antitubercular agents

Abstract: In the present investigation, a series of bicyclic [2-(2,4-dimethylphenylthio)phenyl] aniline analogues were synthesized and characterized by IR, NMR (1H and 13C) and mass spectra. All newly synthesized 15 compounds were inspected for their in vitro antitubercular activity against Mycobacterium tuberculosis (MTB) H 37Ra in both active and dormant state using an established XTT Reduction Menadione assay (XRMA). The titled compounds exhibited minimum inhibitory concentration (MIC90) ranging from 0.05 to?>30 (μ g/mL). The potent four compounds were further evaluated in THP-1 infection model where they demonstrated significant antitubercular activity. All the ex vivo active were further evaluated for cytotoxic activity against THP-1, MCK-7 and HeLa cell lines in order to check selectivity index. All compounds were further screened against four different bacteria to assess their selectivity towards MTB. These derivatives could be considered as a precursor structure for further design of antituberculosis agent. Graphical Abstract: SYNOPSIS A series of bicyclic [2-(2,4-dimethylphenylthio)phenyl] aniline analogues were synthesized. All newly synthesized 15 compounds were inspected for their in vitro antitubercular activity against Mycobacterium tuberculosis (MTB) H 37Ra in both active and dormant state using an established XTT Reduction Menadione assay (XRMA).[Figure not available: see fulltext.].