89817-00-5Relevant academic research and scientific papers
Synthesis of quinoxaline analogues
Chang, Meng-Yang,Lee, Tein-Wei,Hsu, Ru-Ting,Yen, Tzu-Lin
experimental part, p. 3143 - 3151 (2011/10/30)
Substituted tricyclic or tetracyclic quinoxalines, tricyclic pyridoquinoxalines and bis-quinoxalines were synthesized in high yields starting from cyclic ketones by the -bromination of cyclic ketones with N-bromosuccinimide (NBS) followed by condensation of the resulting -bromo ketones with 1,2-diaminobenzene, 3,4-diaminopyridine, or 3,3-diaminobenzidine. Georg Thieme Verlag Stuttgart New York.
Synthesis, crystal structure and cytotoxicity of new oxaliplatin analogues indicating that improvement of anticancer activity is still possible
Galanski, Markus,Yasemi, Afshin,Slaby, Susanna,Jakupec, Michael A.,Arion, Vladimir B.,Rausch, Monika,Nazarov, Alexey A.,Keppler, Bernhard K.
, p. 707 - 714 (2007/10/03)
Oxaliplatin, (trans-R,R-cyclohexane-1,2-diamine)oxalatoplatinum(II), has recently been approved for combination chemotherapy of metastatic colorectal cancer. Oxaliplatin is significantly more active than its trans-S,S isomer and the mixture of both enanti
