898227-93-5

Basic information

• Product Name: 5-ETHYL-1,3-OXAZOLE-4-CARBOXYLIC ACID
• Synonyms: 5-ETHYL-1,3-OXAZOLE-4-CARBOXYLIC ACID;5-ethyloxazole-4-carboxylic acid;5-ethyl-1,3-oxazole-4-carboxylic acid(SALTDATA: FREE)
• CAS NO: 898227-93-5
• Molecular Formula: C6H7NO3
• Molecular Weight: 141.13
• Mol File: 898227-93-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 269.7°C at 760 mmHg
• Flash Point: 116.9°C
• Appearance: /
• Density: 1.273g/cm³
• Vapor Pressure: 0.00353mmHg at 25°C
• Refractive Index: 1.509
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 5-ETHYL-1,3-OXAZOLE-4-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 5-ETHYL-1,3-OXAZOLE-4-CARBOXYLIC ACID(898227-93-5)
• EPA Substance Registry System: 5-ETHYL-1,3-OXAZOLE-4-CARBOXYLIC ACID(898227-93-5)

Safety Data

• Hazardous Substances Data: 898227-93-5(Hazardous Substances Data)

Usage

General Description

5-ETHYL-1,3-OXAZOLE-4-CARBOXYLIC ACID is a chemical compound with the molecular formula C6H7NO3. It is a derivative of oxazole and carboxylic acid, containing an ethyl group at the 5-position of the oxazole ring. 5-ETHYL-1,3-OXAZOLE-4-CARBOXYLIC ACID is used as a building block in organic synthesis and pharmaceutical research. It has potential applications in the development of new drugs and agrochemicals. 5-ETHYL-1,3-OXAZOLE-4-CARBOXYLIC ACID is a white crystalline solid with a melting point of around 122-124°C and is sparingly soluble in water. It is important for its role as a precursor in the synthesis of various bioactive compounds.

InChI:InChI=1/C6H7NO3/c1-2-4-5(6(8)9)7-3-10-4/h3H,2H2,1H3,(H,8,9)

Upstream product

• 32968-45-9 ethyl 5-ethyl-1,3-oxazole-4-carboxylate 

Relevant articles and documents

Widely Exploited, Yet Unreported: Regiocontrolled Synthesis and the Suzuki–Miyaura Reactions of Bromooxazole Building Blocks

An approach to synthesis of 2-, 4-, and 5-bromooxazoles is described. The method was optimized, and its scope was extended to all three isomeric parents, as well as various alkyl- and aryl-substituted bromooxazoles. It was found that direct regiocontrolled lithiation followed by reaction with electrophilic bromine source was common for all substrates and led exclusively to the target substituted 2-, 4- and 5-bromooxazoles on multigram scale. The utility of the multipurpose building blocks obtained in this work was demonstrated in the Suzuki–Miyaura cross-coupling reaction under parallel synthesis conditions.

NOVEL PYRIDINE COMPOUNDS

The present invention relates to certain novel pyridin compounds of Formula ( I ) to processes for preparing such compounds, to their utility as P2Y12 inhibitors and as anti-trombotic agents etc, and processes for their preparation, their use as medicaments in cardiovascular diseases as well as pharmaceutical compositions containing them.