89844-80-4Relevant academic research and scientific papers
REACTION OF ACETYLENE NITRILES WITH AZIDES
Vereshchagin, L. I.,Filippova, T. M.,Bol'shedovorskaya, R. L.,Gavrilov, L. D.,Pavlova, G. A.
, p. 128 - 132 (2007/10/02)
The addition of organic and inorganic azides to 3-phenylpropynenitrile and 4-phenyl-2-hydroxy-3-butynenitrile was investigated.It was shown that organic azides add to 3-phenylpropynenitrile exclusively at the triple bond.The reaction with aluminum azide takes place with the participation of the acetylene bond and the nitrile group.The reaction of 4-phenyl-2-hydroxy-3-butynenitrile with azides is accompanied by decomposition to phenylpropargylaldehyde with the subsequent formation of 4-formyl-1,2,3-triazole.The oxidation of 4-phenyl-2-hydroxy-3-butynenitrile withactive manganese dioxide with the simultaneous addition of the azides leads to the formation of 4-carboxy-5-phenyl-1,2,3-triazole.
