89849-82-1Relevant articles and documents
Acylphosphonates. 5. A new method for Stereospecific Generation of Phosphorothioate via Aroylphosphonate Intermediate
Fujii, Mitsuo,Ozaki, Kouji,Kume, Akiko,Sekine, Mitsuo,Hata, Tsujiaki
, p. 935 - 938 (2007/10/02)
Dideoxynucleoside phosphorothioates were synthesized by a new mwthod via dideoxynucleoside aroylphosphonates.The aroyl groups were easily removed from 1 and 2 by the action of n-BuNH2 and in situ converted to only one diastereomer (Rp configura
Acylphosphonates. 4. Synthesis of Dithymidine Phosphonate: A New Method for Generation of Phosphonate Function via Aroylphosphonate Intermediates
Kume, Akiko,Fujii, Mitsuo,Sekine, Mitsuo,Hata, Tsujiaki
, p. 2139 - 2143 (2007/10/02)
Dithymidine phosphonate (10) was synthesized by a new method via dithymidine aroylphosphonates (3) in which the aroyl group served as a protecting group for O=P-H functions.In a way analogous to the phosphotriester method, 3 was prepared by successive con