898509-58-5

Upstream product

• 96-50-4 2-thiazolylamine 
• 61767-34-8 2-(4-methylphenyl)-4-dichloromethylideneoxazol-5(4H)-one 

Downstream Products

• 1120362-91-5 2-(4-methylphenyl)-5-(piperidin-1-yl)-N-(1,3-thiazol-2-yl)-1,3-oxazol-4-carboxamide 

Relevant academic research and scientific papers

Successive reaction of 2-aryl-4-dichloromethylideneoxazol-54H-ones with 2-amino-1,3-thiazoles and strongly basic nitrogen-containing reagents

Treatment of 2-aryl-4-dichloromethylideneoxazole-5(4H)-ones first with 2-aminothiazoles and then with benzylamine, piperidine, or morpholine gave the corresponding 5-amino-4-(1,3-thiazol-2-ylcarbamoyl)-1,3-oxazole derivatives whose structure was confirmed by a combination of spectral data and X-ray analysis.