898533-72-7Relevant academic research and scientific papers
Discovery of a new class of potential multifunctional atypical antipsychotic agents targeting dopamine d3 and serotonin 5-HT 1A and 5-HT2A receptors: Design, synthesis, and effects on behavior
Butini, Stefania,Gemma, Sandra,Campiani, Giuseppe,Franceschini, Silvia,Trotta, Francesco,Borriello, Marianna,Ceres, Nicoletta,Ros, Sindu,Coccone, Salvatore Sanna,Bernetti, Matteo,De Angelis, Meri,Brindisi, Margherita,Nacci, Vito,Fiorini, Isabella,Novellino, Ettore,Cagnotto, Alfredo,Mennini, Tiziana,Sandager-Nielsen, Karin,Andreasen, Jesper Tobias,Scheel-Kruger, Jorgen,Mikkelsen, Jens D.,Fattorusso, Caterina
experimental part, p. 151 - 169 (2009/09/25)
Dopamine D3 antagonism combined with serotonin 5-HT1A and 5-HT2A receptor occupancy may represent a novel paradigm for developing innovative antipsychotics. The unique pharmacological features of 5i are a high affinity for
