898533-73-8Relevant academic research and scientific papers
Synthesis and antitumor activity of 2-aryl-1, 2, 4-triazolo[1, 5-a] pyridine derivatives
Tao, Xuefen,Hu, Yongzhou
experimental part, p. 65 - 69 (2011/12/14)
A novel series of 2-aryl-1, 2, 4-triazolo [1, 5-a] pyridine derivatives have been synthesized and evaluated for their cytotoxic activities in vitro against Human ovarian cancer cell line (HO-8910) and Human liver cancer cell line (Bel 7402). Most compounds showed high or mediate activity against the cancer cell lines when compared with Cisplatin. Two of them were tested the apoptosis on Bel 7402.
Synthesis and antitumor activities of 2-(substituted)phenyl-1,2,4- triazolo[1,5-a]pyridines
Zhang, Guolin,Hu, Yongzhou
, p. 919 - 922 (2008/03/29)
(Chemical Equation Presented) Twenty-three 2-(substituted)phenyl-1,2,4- triazolo[1,5-a]pyridines have been synthesized by cyclo-additison reaction between N-amino methylpyridinium mesitylenesulfonates and substituted benzonitriles under the presence of po
Synthesis and antifungal activity of 2-aryl-1,2,4-triazolo[1,5-a]pyridine derivatives
Luo, Yun,Hu, Yongzhou
, p. 262 - 266 (2007/10/03)
A series of novel antifungal triazole derivatives 2-aryl-1,2,4-triazolo[1, 5-a]pyridine 9a-m were synthesized and tested in vitro for their growth inhibitory activities against C. albicans and T. rubrum. The MIC values indicate that the activities of three compounds were superior or comparable to fluconazole against both tested fungi, worthy of further investigation of its antifungal activities.
