898559-24-5

Basic information

• Product Name: 3-BROMOQUINOLINE-2-CARBALDEHYDE
• Synonyms: 3-BROMOQUINOLINE-2-CARBALDEHYDE
• CAS NO: 898559-24-5
• Molecular Formula: C10H6BrNO
• Molecular Weight: 236.06474
• Mol File: 898559-24-5.mol
• Article Data: 5

Chemical Properties

• Melting Point: 110-111 °C
• Boiling Point: 341.4±22.0 °C(Predicted)
• Appearance: /
• Density: 1.632±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 1.18±0.50(Predicted)
• CAS DataBase Reference: 3-BROMOQUINOLINE-2-CARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BROMOQUINOLINE-2-CARBALDEHYDE(898559-24-5)
• EPA Substance Registry System: 3-BROMOQUINOLINE-2-CARBALDEHYDE(898559-24-5)

Safety Data

• Hazardous Substances Data: 898559-24-5(Hazardous Substances Data)

Usage

General Description

3-Bromoquinoline-2-carbaldehyde is a chemical compound with the formula C11H7BrNO. It is a yellow solid that is commonly used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. 3-Bromoquinoline-2-carbaldehyde is also known for its use in organic chemistry and as a building block for the construction of complex molecules. It is a versatile reagent in the field of chemical synthesis and is often employed in the preparation of heterocyclic compounds. Additionally, 3-Bromoquinoline-2-carbaldehyde exhibits antimicrobial and antitumor properties, making it a subject of interest in medicinal chemistry research. Overall, this chemical compound plays a crucial role in the development and production of various important molecules with promising biological activities.

Upstream product

• 68-12-2 N,N-dimethyl-formamide 
• 5332-24-1 3-bromoquinoline 

Relevant articles and documents

HETEROARYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS

Described herein are heteroaryl compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions and medicaments that include the heteroaryl compounds described. Also described herein are methods of using such antagonists o

PREPARATION AND USE OF MAGNESIUM AMIDES

The present application relates to mixed Mg/Li amides of the general formula R1R2N-Mg-NR3R4.zLiY (II) wherein R1, R2, R3, and R4 are, independently, selected from H, substituted or unsubstituted aryl or heteroaryl containing one or more heteroatoms, linear, branched or cyclic, substituted or unsubstituted alkyl, alkenyl, alkynyl, or silyl derivatives thereof; and R1 and R2 together, or R3 and R4 together can be part of a cyclic or polymeric structure; and wherein at least one of R1 and R2 and at least one of R3 and R4 is other than H; Y is selected from the group consisting of F; Cl; Br; I; CN; SCN; NCO; HaIOn, wherein n = 3 or 4 and Hal is selected from Ci, Br and I; NO3; BF4; PF6; H; a carboxylate of the general formula RxCO2; an alcoholate of the general formula ORx; a thiolate of the general formula SRx; RxP(O)O2; or SCORx; or SCSRx; OnSRx, wherein n = 2 or 3; or NOn, wherein n = 2 or 3; and a derivative thereof; wherein Rx is a substituted or unsubstituted aryl or heteroaryl containing one or more heteroatoms, linear, branched or cyclic, substituted or unsubstituted alkyl, alkenyl, alkynyl, or derivatives thereof, or H; m is O or 1; and z > 1; as well as a process for the preparation of the mixed Mg/Li amides and the use of these amides, e.g. as bases.

Mixed Mg/Li amides of the type R2NMgCl·LiCl as highly efficient bases for the regioselective generation of functionalized aryl and heteroaryl magnesium compounds

(Chemical Equation Presented) Two are better than one: Mixed lithium-magnesium complexes of the type R2NMgCl·LiCl are kinetically highly active bases that convert a range of polyfunctional aromatic and heteroaromatic substrates into the corresponding magnesiated derivatives with high regioselectivity.