898764-30-2Relevant academic research and scientific papers
Alkylation synthesis method of in-situ catalytic alcohol (by machine translation)
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Paragraph 0099-0101; 0138-0140, (2020/11/01)
The method comprises VIB metal complexes, an auxiliary ligand and a base as a catalytic reaction system, wherein the alcohol serves as an alkylating agent, and the nucleophilic substrate is subjected to in-situ catalytic alkylation reaction in a solvent and an inert gas atmosphere. The catalytic system has a wide application range on a substrate, can catalyze the synthesis of C-N and C-C bond compounds of different structures under mild conditions, and can green synthesize a series of valuable N - alkylation and C - alkylation compounds. (by machine translation)
Nonbifunctional Outer-Sphere Strategy Achieved Highly Active α-Alkylation of Ketones with Alcohols by N-Heterocyclic Carbene Manganese (NHC-Mn)
Lan, Xiao-Bing,Ye, Zongren,Huang, Ming,Liu, Jiahao,Liu, Yan,Ke, Zhuofeng
supporting information, p. 8065 - 8070 (2019/10/11)
The unusual nonbifunctional outer-sphere strategy was successfully utilized in developing an easily accessible N-heterocyclic carbene manganese (NHC-Mn) system for highly active α-alkylation of ketones with alcohols. This system was efficient for a wide range of ketones and alcohols under mild reaction conditions, and also for the green synthesis of quinoline derivatives. The direct outer-sphere mechanism and the high activity of the present system demonstrate the potential of nonbifunctional outer-sphere strategy in catalyst design for acceptorless dehydrogenative transformations.
Unexpected formation of aryl ketones by palladium-catalyzed coupling of aryl bromides with vinylic acetates
Jean, Mickael,Renaulty, Jacques,Uriac, Philippe,Capet, Marc,Van De Weghe, Pierre
, p. 3623 - 3625 (2008/02/12)
A palladium-catalyzed coupling reaction of aryl bromides with vinylic acetates in the presence of tributyitin methoxide has been described. Unexpected formation of aryl ketones was obtained. Preliminary mechanistic studies indicated that the reaction proceeded by the addition of the aryl moiety in the coordination sphere of palladium to a ketene.
