898766-45-5Relevant academic research and scientific papers
Palladium-catalyzed ortho-selective C-H bond chlorination of aromatic ketones
Shan, Gang,Huang, Gui-Yi,Rao, Yu,Zhang, Hui
, p. 1236 - 1240 (2015)
A palladium-catalyzed ortho-selective C-H bond chlorination reaction for the preparation of 2-chloro aromatic ketones was described. Both electron-withdrawing and electron-donating groups on the aromatic rings are well tolerated under the optimized conditions. The 2-chloro aromatic ketones obtained by our method could be applied to synthesize the derivatives of 1H-indazole or benzo[d]isoxazole.
