898785-23-4

Basic information

• Product Name: 5-CHLORO-1-(3-METHYLPHENYL)-1-OXOPENTANE
• Synonyms: 5-CHLORO-1-(3-METHYLPHENYL)-1-OXOPENTANE
• CAS NO: 898785-23-4
• Molecular Formula: C12H15ClO
• Molecular Weight: 210.7
• Mol File: 898785-23-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 327.8°C at 760 mmHg
• Flash Point: 180.8°C
• Appearance: /
• Density: 1.063g/cm³
• Vapor Pressure: 0.000197mmHg at 25°C
• Refractive Index: 1.516
• CAS DataBase Reference: 5-CHLORO-1-(3-METHYLPHENYL)-1-OXOPENTANE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-CHLORO-1-(3-METHYLPHENYL)-1-OXOPENTANE(898785-23-4)
• EPA Substance Registry System: 5-CHLORO-1-(3-METHYLPHENYL)-1-OXOPENTANE(898785-23-4)

Safety Data

• Hazardous Substances Data: 898785-23-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H15ClO/c1-10-5-4-6-11(9-10)12(14)7-2-3-8-13/h4-6,9H,2-3,7-8H2,1H3

Upstream product

• 138344-21-5 4-Chloro-N,O-dimethylbutyric acid amide 
• 28987-79-3 m-tolylmagnesium bromide 
• 1575-61-7 5-Chlorovaleroyl chloride 

Downstream Products

• 1452523-63-5 (R_S,R)-N-(tert-butylsulfinyl)-2-(3-methylphenyl)piperidine 
• 1452523-47-5 (R)-N-[5-chloro-1-(3-methylphenyl)pentylidene]-2-methylpropane-2-sulfinamide 

Relevant articles and documents

Synthesis of nitrogenated heterocycles by asymmetric transfer hydrogenation of N-(tert-butylsulfinyl)haloimines

Highly optically enriched, protected, nitrogenated heterocycles with different ring sizes have been synthesized by a very efficient methodology consisting of the asymmetric transfer hydrogenation of N-(tert-butylsulfinyl) haloimines followed by treatment with a base to promote an intramolecular nucleophilic substitution process. N-Protected aziridines, pyrrolidines, piperidines, and azepanes bearing aromatic, heteroaromatic, and aliphatic substituents have been obtained in very high yields and diastereomeric ratios up to >99:1. The free heterocycles can be easily obtained by a simple and mild desulfinylation procedure. Both enantiomers of the free heterocycles can be prepared with the same good results by changing the absolute configuration of the sulfur atom of the sulfinyl group.