898801-54-2Relevant academic research and scientific papers
Synthetic routes to three novel scaffolds for potential glycosidase inhibitors
Rommel, Michael,Ernst, Alexander,Koert, Ulrich
, p. 4408 - 4430 (2008/09/17)
Efficient syntheses of three novel scaffolds for potential β-glycosidase inhibitors were developed: The first consists of a 2,7-dioxabicyclo[2.2.1]heptane derivative, which was prepared by an intramolecular ketalisation. The second scaffold consists of a
Synthesis of novel bicyclic ketals of galacturonic acid as potential glycosidase inhibitors
Rommel, Michael,Ernst, Alexander,Harms, Klaus,Koert, Ulrich
, p. 1067 - 1070 (2007/10/03)
A synthesis of novel bicyclic ketals of galacturonic acid is described. The key cyclisation step was realised under acidic anhydrous conditions in very good yield. X-ray crystal structure analysis determined the correct regio- and stereochemistry. Georg T
