89894-13-3Relevant academic research and scientific papers
MODULATORS OF THE INTEGRATED STRESS PATHWAY
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, (2019/05/22)
Provided herein are compounds, compositions, and methods useful for the modulation of elF2B, for modulating the integrated stress response (ISR) and for treating related diseases; disorders and conditions.
INHIBITORS OF INTEGRATED STRESS RESPONSE PATHWAY
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, (2019/12/28)
The present disclosure relates generally to therapeutic agents that may be useful as inhibitors of Integrated Stress Response (ISR) pathway.
MODULATORS OF THE INTEGRATED STRESS PATHWAY
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, (2017/12/14)
Provided herein are compounds, compositions, and methods useful for modulating the integrated stress response (ISR) and for treating related diseases; disorders and conditions.
SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME
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Page/Page column 125, (2015/07/07)
Disclosed are novel substituted amino triazoles of Formula (I), and pharmaceutically acceptable salts thereof. The compounds of Formula (I) are inhibitors of Acidic mammalian chitinase (AMCase) and are useful, in a non-limiting example, for treating asthma. Also provided are pharmaceutical compositions containing at least one compound of the present invention, or a pharmaceutically acceptable salt, hydrate or solvate thereof, and at least one pharmaceutically acceptable carrier, solvent, adjuvant or diluent, and methods of using such compounds and/or compositions to treat asthma and/or to monitor asthma treatment.
