89894-80-4Relevant academic research and scientific papers
The Photochemical Activity of a Halogen-Bonded Complex Enables the Microfluidic Light-Driven Alkylation of Phenols
Cuadros, Sara,Rosso, Cristian,Barison, Giorgia,Costa, Paolo,Kurbasic, Marina,Bonchio, Marcella,Prato, Maurizio,Filippini, Giacomo,Dell'Amico, Luca
supporting information, p. 2961 - 2966 (2022/05/02)
A mild light-driven protocol for the direct alkylation of phenols is reported. The process is driven by the photochemical activity of a halogen-bonded complex formed upon complexation of the in situ generated electron-rich phenolate anion with the α-iodosulfone. The reaction proceeds rapidly (10 min) under microfluidic conditions, delivering a wide variety of ortho-alkylated products (27 examples, up to 97% yield, >20:1 regioselectivity, on a gram scale), including densely functionalized bioactive phenol derivatives.
An Efficient Synthesis of α-Iodo Derivatives of Sulfones, Sulfoximines, and Phosphine Oxides
Imamoto, Tsuneo,Koto, Hiroyasu
, p. 982 - 983 (2007/10/02)
1-Iodoalkyl sulfones are prepared by conversion of alkyl sulfones into 1-sulfonylalkyltriethylalanates by reaction with butyllithium and triethylalane and subsequent reaction with iodine.The same method can be applied to the conversion of methyldiarylphos
