89899-11-6Relevant academic research and scientific papers
Modulating weak interactions for molecular recognition: A dynamic combinatorial analysis for assessing the contribution of electrostatics to the stability of CH-π bonds in water
Jiménez-Moreno, Ester,G?mez, Ana M.,Bastida, Agatha,Corzana, Francisco,Jiménez-Oses, Gonzalo,Jiménez-Barbero, Jesús,Asensio, Juan Luis
supporting information, p. 4344 - 4348 (2015/04/14)
Electrostatic and charge-transfer contributions to CH-π complexes can be modulated by attaching electron-withdrawing substituents to the carbon atom. While clearly stabilizing in the gas phase, the outcome of this chemical modification in water is more difficult to predict. Herein we provide a definitive and quantitative answer to this question employing a simple strategy based on dynamic combinatorial chemistry.
Piperazine derivatives for treatment of bacterial infections
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, (2008/06/13)
Piperazine derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly in man.
