899-26-3Relevant academic research and scientific papers
Selective one-pot synthesis of symmetrical and unsymmetrical di- and triarylamines with a ligandless copper catalytic system
Tlili, Anis,Monnier, Florian,Taillefer, Marc
supporting information; experimental part, p. 6408 - 6410 (2012/07/27)
The one-pot synthesis of symmetrical or unsymmetrical di- or triarylamines using aryl iodides or bromides and LiNH2 as ammonia source is reported. This highly selective method is based, for the first time, on a copper-catalyzed system, which does not require the presence of any additional ligand.
Selective palladium-catalyzed arylation of ammonia: Synthesis of anilines as well as symmetrical and unsymmetrical di- and triarylamines
Surry, David S.,Buchwald, Stephen L.
, p. 10354 - 10355 (2008/03/13)
It is shown that by selection of an appropriate palladium/ligand system, temperature, concentration, and stoichiometry of reagents, ammonia may be selectively arylated to give either anilines, symmetrical di-, or triarylamines. Furthermore different aryl halides may be added sequentially to the reaction mixture, allowing the synthesis of unsymmetrical di- and triarylamines from aryl halides and ammonia in a one-pot protocol Copyright
