899-79-6Relevant articles and documents
Zn-Mediated Hydrodeoxygenation of Tertiary Alkyl Oxalates
Ye, Yang,Ma, Guobin,Yao, Ken,Gong, Hegui
, p. 1625 - 1628 (2021/01/18)
Herein we describe a general, mild, and scalable method for hydrodeoxygenation of readily accessible tertiary alkyl oxalates by Zn/silane under Ni-catalyzed conditions. The reduction method is suitable for an array of structural motifs derived from tertiary alcohols that bear diverse functional groups, including the synthesis of a key intermediate en route to estrone.
Desymmetrization of cyclic 1,3-diketones via Ir-catalyzed hydrogenation: An efficient approach to cyclic hydroxy ketones with a chiral quaternary carbon
Gong, Quan,Wen, Jialin,Zhang, Xumu
, p. 6350 - 6353 (2019/07/04)
We herein report an efficient method to synthesize cyclic hydroxy ketones with a chiral quaternary center. Catalyzed by an Ir/f-ampha complex, cyclic α,α-disubstituted 1,3-diketones were hydrogenated, giving mono-reduced products with both high enantiosel
Pentacyclic compounds by samarium diiodide-induced cascade cyclizations of naphthyl-substituted 1,3-diones
Wefelscheid, Ulrike K.,Reissig, Hans-Ulrich
supporting information; scheme or table, p. 65 - 69 (2009/04/06)
Treatment of naphthyl-substituted cyclopentane-1,3-diones with the samarium diiodidehexamethylphosphoramide (HMPA) complex in the presence of tert-butyl alcohol provided the expected tetracyclic diols with steroid-like structures. Surprisingly, reactions