89909-50-2Relevant academic research and scientific papers
A meso-unsubstituted N-confused porphyrin prepared by rational synthesis
Liu, Ben Y.,Brueckner, Christian,Dolphin, David
, p. 2141 - 2142 (2007/10/03)
Condensation of a tetraalkyl-α,α-dipyrromethane dialdehyde in a MacDonald-type [2+2]-condensation with a trialkyl-α,β-dipyrromethane gives a heptaalkyl N-confused porphyrin.
Total Syntheses of Derivatives of Protoporphyrin IX Regioselectively Labeled with Carbon-13 in the Methyls
Smith, Kevin M.,Fujinari, Eugene M.,Pandey, Ravindra K.,Tabba, Hani D.
, p. 4667 - 4676 (2007/10/02)
Total syntheses, from monopyrroles via tripyrrenes and a,c-biladienes, of the four isomers 2-5 of protoporphyrin IX dimethyl ester in which the 1-, 3-, 5-, and 8-methyl groups are individually and regioselectively enriched with carbon-13 are described.The source of labeled carbon was 90percent carbon-13-enriched paraformaldehyde, and methyls were inserted at the monopyrrole stage by reductive C-alkylation.The carbon-13-labeled porphyrins, as the corresponding hemes, are of interest as probes in carbon-13 NMR spectroscopic studies of reconstituted heme proteins.
