899371-99-4

Basic information

• Product Name: 2-amino-4-(4-hydroxyphenyl)-5,10-dioxo-5,10-dihydro-4H-benzo[g]chromene-3-carbonitrile
• Synonyms: 2-amino-4-(4-hydroxyphenyl)-5,10-dioxo-5,10-dihydro-4H-benzo[g]chromene-3-carbonitrile
• CAS NO: 899371-99-4
• Molecular Weight: 344.326
• Mol File: 899371-99-4.mol

Chemical Properties

• CAS DataBase Reference: 2-amino-4-(4-hydroxyphenyl)-5,10-dioxo-5,10-dihydro-4H-benzo[g]chromene-3-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-4-(4-hydroxyphenyl)-5,10-dioxo-5,10-dihydro-4H-benzo[g]chromene-3-carbonitrile(899371-99-4)
• EPA Substance Registry System: 2-amino-4-(4-hydroxyphenyl)-5,10-dioxo-5,10-dihydro-4H-benzo[g]chromene-3-carbonitrile(899371-99-4)

Safety Data

• Hazardous Substances Data: 899371-99-4(Hazardous Substances Data)

Upstream product

• 83-72-7 2-hydroxynaphtho-1,4-quinone 
• 123-08-0 4-hydroxy-benzaldehyde 
• 109-77-3 malononitrile 

Relevant articles and documents

Magnetite nanoparticles-supported APTES as a powerful and recoverable nanocatalyst for the preparation of 2-amino-5,10-dihydro-5,10-dioxo-4H-benzo[g]chromenes and tetrahydrobenzo[g]quinoline-5,10-diones

Aim and Objective: This study introduces a green and effective approach for the preparation of biologically-active heterocyclic compounds including 2-amino-5,10-dihydro-5,10-dioxo-4H-benzo[g]chromenes and tetrahydrobenzo[g]quinoline-5,10-diones using one-

Synthesis of pyridinium-based salts: Catalytic application at the synthesis of six membered O-heterocycles

In this paper, a range of pyridinium-based ionic liquid (IL) and molten salts (MSs) with various counter ions were designed, synthesized and fully characterized. These novel ionic liquid and molten salts were prepared via the reaction of [PySO3

Application of cobalt phthalocyanine as a nanostructured catalyst in the synthesis of biological henna-based compounds

The present investigation describes synthesis of a good range of henna-based compounds in the presence of novel nano cobalt phthalocyanine like molten salt (tetra-2,3-pyridiniumporphyrazinato cobalt tribromomethanide) [Co (TPPABr)]CBr3 as an efficient, recyclable and thermally stable heterogeneous catalyst.

A method for the preparation of substituted benzo [g] benzopyran derivatives

The invention discloses a method for catalytically preparing a 2-amino-3-cyano-4-aryl-5,10-dioxo-5,10-dihydro-4H-benzo[g]chromene derivative and belongs to the technical field of organic chemical engineering. In preparation reaction, the mole ratio of aro

Piperidine-Promoted Three-Component Condensation: Synthesis of Chromene Heterocycles and Pyrazolotriazoles

Chromenes, the oxygen-containing heterocyclic compounds, have a “special” place in biologically active natural products and in synthetic chemistry and in the fields of medicinal, agrochemical, cosmetic, and pigment industries. In this work, piperidine was used as a base catalyst for the convenient synthesis of 1,4-dihydropyrano[2,3-c]pyrazole, 5,10-dihydro-4H-benzo[g]chromene, and pyrazolo[1,2-a] [1,2,4]triazole derivatives at ambient temperature. This methodology has several advantages including the use of easily accessible and inexpensive catalysts, short reaction times, high yields, convenient work-up, and not needing column chromatography.

Zn(L -proline)2 as a powerful and reusable organometallic catalyst for the very fast synthesis of 2-amino-4H-benzo[g]chromene derivatives under solvent-free conditions

An efficient route for the synthesis of 2-amino-4H-benzo[g]chromenes via a three-component coupling reaction of aldehydes, malononitrile and 2-hydroxy-1,4-naphthaquinone in the presence of Zn(L-proline)2 is reported. High yields, short reaction

Silica-bonded propylpiperazine-N-sulfamic acid as recyclable solid acid catalyst for preparation of 2-amino-3-cyano-4-aryl-5,10-dioxo- 5,10-dihydro-4H-benzo[g]chromenes and hydroxy-substituted naphthalene-1,4-dione derivatives

An efficient method for the synthesis of 2-amino-3-cyano-4-aryl-5,10-dioxo- 5,10-dihydro-4H-benzo[g]chromenes and hydroxy-substituted naphthalene-1,4-dione derivatives, using silica-bonded propylpiperazine-N-sulfamic acid as a solid acid, green, heterogeneous catalyst, under ambient and solvent-free conditions, is described. A simple procedure, high yields, short reaction time, safety, and reusability of the catalyst are advantages of these protocols.

Potassium phthalimide-N-oxyl: A novel, efficient, and simple organocatalyst for the one-pot three-component synthesis of various 2-amino-4H-chromene derivatives in water

A wide variety of 2-amino-4H-chromene derivatives with diverse substituents on the 4H-chromene ring were efficiently prepared via one-pot, three-component reaction of an aromatic aldehyde, malononitrile (or ethyl cyanoacetate), and diverse enolizable C-H activated acidic compounds in the presence of low loading of potassium phthalimide-N-oxyl (POPINO), as a new organocatalyst, in aqueous media. This procedure is a clean, transition metal-free, and environmentally friendly approach to prepare different 2-amino-4H-chromen derivatives that offers many advantages including short reaction time, high to quantitative yields, low cost, and straightforward work-up.

Effective preparation of 2-amino-3-cyano-4-aryl-5,10-dioxo-5,10-dihydro-4H- benzo[g]chromene and hydroxyl naphthalene-1,4-dione derivatives under ambient and solvent-free conditions

The mild basic ionic liquids, 1,8-diazabicyclo[5.4.0]-undec-7-en-8-ium acetate, pyrrolidinium acetate, pyrrolidinium formate, piperidinium acetate, piperidinium formate, N-methylimidazolium formate, and 3-hydroxypropanaminium acetate catalyzed three-component synthesis of 2-amino-3-cyano-4-aryl-5,10- dioxo-5,10-dihydro-4H-benzo[g]chromene and hydroxyl naphthalene-1,4-dione derivatives under ambient and solvent-free conditions. Simple procedure, high yields, short reaction time and environmentally benign method are advantages of these protocols. The inexpensive and non-toxic ionic liquids can be reused several times without noticeable loss of their activities. The mentioned ionic liquids show priority relative to other catalysts in the literature.