899437-06-0Relevant academic research and scientific papers
Syntheses of ring-fluorinated isoquinolines and quinolines via intramolecular substitution: Cyclization of 1,1-difluoro-1-alkenes bearing a sulfonamide moiety
Ichikawa, Junji,Sakoda, Kotaro,Moriyama, Hiroko,Wada, Yukinori
, p. 1590 - 1598 (2007/10/03)
On treatment of a base such as NaH, KH, or Et3N, N-[o-(2,2-difluorovinyl)benzyl]- and N-[o-(3,3-difluoroallyl)phenyl]-substituted p-toluenesulfonamides readily undergo intramolecular substitution of sulfonamide nitrogens for vinylic fluorines i
