89947-90-0Relevant academic research and scientific papers
Efficient site-specific cleavage of RNA using a terpyridine-copper(II) complex joined to a 2'-O-methyloligonucleotide by a non-flexible linker
Inoue, Hideo,Furukawa, Takako,Shimizu, Masaki,Tamura, Takashi,Matsui, Miwa,Ohtsuka, Eiko
, p. 45 - 46 (2007/10/03)
A terpyridine-Cu(II) complex conjugated to an antisense 2'O-methyloligonucleotide at the 5'-end cleaved RNA predominantly at the site opposite the 5'-end in moderate yield, but the cleavage yield increased by more than two-fold when a 2'-O-methyloligonucl
Site-specific RNA cleavage using terpyridine · Cu(II)-linked 2'-O- methyloligonucleotides
Inoue, Hideo,Shimizu, Masaki,Furukawa, Takako,Tamura, Takashi,Matsui, Miwa,Ohtsuka, Eiko
, p. 1503 - 1505 (2007/10/03)
2'-Deoxy- and 2'-O-methyl-5'-O-terpyridyl derivatives of adenosine and cytidine were synthesized and used to construct 5'-end-modified oligonucleotides. These antisense agents complexed with Cu(II) exclusively cleaved a complementary RNA oligomer at the s
STEREOSPECIFIC SYNTHESIS OF DINUCLEOSIDE MONOPHOSPHATE ARYL ESTERS BY USING NEW CONDENSING REAGENTS
Ohtsuka, Eiko,Shiraishi, Masahiko,Ikehara, Morio
, p. 365 - 368 (2007/10/02)
New condensing reagents, arenesulfonyl 5-(pyridin-2-yl)tetrazoles have been synthesized and used for stereospecific synthesis of dinucleoside monophosphate aryl esters.
