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899798-68-6

(2R,3S)-5-(tert-Butyl-diphenyl-silanyloxy)-1-((1S,5R,7R)-10,10-dimethyl-3,3-dioxo-3λ6-thia-4-aza-tricyclo[5.2.1.01,5]dec-4-yl)-3-methoxymethoxy-2-methyl-pentan-1-one is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • (2R,3S)-5-(tert-Butyl-diphenyl-silanyloxy)-1-((1S,5R,7R)-10,10-dimethyl-3,3-dioxo-3λ6-thia-4-aza-tricyclo[5.2.1.01,5]dec-4-yl)-3-methoxymethoxy-2-methyl-pentan-1-one

    Cas No: 899798-68-6

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  • (2R,3S)-5-(tert-Butyl-diphenyl-silanyloxy)-1-((1S,5R,7R)-10,10-dimethyl-3,3-dioxo-3λ6-thia-4-aza-tricyclo[5.2.1.01,5]dec-4-yl)-3-methoxymethoxy-2-methyl-pentan-1-one

    Cas No: 899798-68-6

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  • 899798-68-6 Structure

  • Basic information

    1. Product Name: (2R,3S)-5-(tert-Butyl-diphenyl-silanyloxy)-1-((1S,5R,7R)-10,10-dimethyl-3,3-dioxo-3λ6-thia-4-aza-tricyclo[5.2.1.01,5]dec-4-yl)-3-methoxymethoxy-2-methyl-pentan-1-one
    2. Synonyms: (2R,3S)-5-(tert-Butyl-diphenyl-silanyloxy)-1-((1S,5R,7R)-10,10-dimethyl-3,3-dioxo-3λ6-thia-4-aza-tricyclo[5.2.1.01,5]dec-4-yl)-3-methoxymethoxy-2-methyl-pentan-1-one
    3. CAS NO:899798-68-6
    4. Molecular Formula:
    5. Molecular Weight: 627.918
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 899798-68-6.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (2R,3S)-5-(tert-Butyl-diphenyl-silanyloxy)-1-((1S,5R,7R)-10,10-dimethyl-3,3-dioxo-3λ6-thia-4-aza-tricyclo[5.2.1.01,5]dec-4-yl)-3-methoxymethoxy-2-methyl-pentan-1-one(CAS DataBase Reference)
    10. NIST Chemistry Reference: (2R,3S)-5-(tert-Butyl-diphenyl-silanyloxy)-1-((1S,5R,7R)-10,10-dimethyl-3,3-dioxo-3λ6-thia-4-aza-tricyclo[5.2.1.01,5]dec-4-yl)-3-methoxymethoxy-2-methyl-pentan-1-one(899798-68-6)
    11. EPA Substance Registry System: (2R,3S)-5-(tert-Butyl-diphenyl-silanyloxy)-1-((1S,5R,7R)-10,10-dimethyl-3,3-dioxo-3λ6-thia-4-aza-tricyclo[5.2.1.01,5]dec-4-yl)-3-methoxymethoxy-2-methyl-pentan-1-one(899798-68-6)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 899798-68-6(Hazardous Substances Data)

899798-68-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 899798-68-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,9,9,7,9 and 8 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 899798-68:
(8*8)+(7*9)+(6*9)+(5*7)+(4*9)+(3*8)+(2*6)+(1*8)=296
296 % 10 = 6
So 899798-68-6 is a valid CAS Registry Number.

899798-68-6Relevant articles and documents

The total synthesis and biological properties of the cytotoxic macrolide FD-891 and its non-natural (Z)-C12 isomer

Garcia-Fortanet, Jorge,Murga, Juan,Carda, Miguel,Marco, J. Alberto,Matesanz, Ruth,Diaz, J. Fernando,Barasoain, Isabel

, p. 5060 - 5074 (2008/02/11)

A total, stereoselective synthesis of the naturally occurring, cytotoxic macrolide FD-891 and of its non-natural (Z)-C12 isomer is described. Three fragments of the main carbon chain were stereoselectively prepared by using asymmetric aldol and allylation reactions as the key steps. The molecule was then assembled by using two Julia-Kocienski olefinations to connect the three fragments and a Yamaguchi reaction to close the macrolactone ring. Some specific biological properties (cytotoxicity, binding to tubulin) have been determined for both macrolides. The E configuration of the C12-C13 olefinic bond seems to be an important feature in determining the cytotoxicity but the precise biological mechanism of the latter still remains to be cleared.

Stereoselective synthesis of the cytotoxic macrolide FD-891

Garcia-Fortanet, Jorge,Murga, Juan,Carda, Miguel,Marco, J. Alberto

, p. 2695 - 2698 (2007/10/03)

A total synthesis of the naturally occurring, cytotoxic macrolide FD-891 is described. Three fragments were first stereoselectively constructed using mainly asymmetric aldol and allylation reactions. The complete framework was then assembled using two Jul

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