89980-69-8Relevant academic research and scientific papers
A total synthesis of (+)-brazilin
Huang, Shuangping,Ou, Wentao,Li, Wang,Xiao, Hesheng,Pang, Yiying,Zhou, Yi,Wang, Xiaoji,Yang, Xihua,Wang, Liping
supporting information, (2020/05/22)
Described herein is a concise total synthesis of (+)-brazilin from readily available 4-bromo-1,2-dimethoxybenzene. In this synthetic route, a Sharpless asymmetric dihydroxylation was employed to introduce the chiral hydroxyl group, and trifluoroacetic acid (TFA) catalyzed one-pot intramolecular tandem Prins/Friedel-Crafts reaction was also involved as the key transformation in the construction of the hybrid chromane and indane framework.
MODULATORS OF CENTRAL NERVOUS SYSTEM NEUROTRANSMITTERS
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Page/Page column 54; 140; 146, (2010/10/20)
Disclosed are agents having pharmacological activity against cellular receptors and intracellular singaling, particularly receptors and sigaling pathways of central nervous system (CNS) neurotransmitters. Also disclosed are related methods and compositions for the treatment or prevention of diseases or disorders using the agents.
2-(PIPERIDIN-4-YL) -4, 5-DIHYDRO-2H-PYRIDAZIN-3-ONE DERIVATIVES AS PDE4 INHIBITORS
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Page/Page column 26, (2008/06/13)
The compounds of a certain formula (1), in which R1, R2, R3 and R9 have the meanings as given in the description, are novel effective PDE4 inhibitors.
Acrylic acid morpholides and fungicidal compositions
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, (2008/06/13)
This invention relates to a compound of the formula: STR1 wherein R1 is hydrogen, a halogen or a lower alkyl group; R2 and R33 independently are a lower alkoxyl group; and Py is an optionally substituted pyridyl group or a salt thereof. The compound or a salt thereof exerts excellent fungicidal effects against plant disease and is used as fungicide for agricultural use.
