89998-48-1

Upstream product

• 3153-36-4 4-chloro-butyric acid ethyl ester 
• 82359-63-5 4-(2,3-Dimethoxyphenyl)-1,2,3,6-tetrahydro-1-methyl-pyridine 
• 1445-73-4 1-Methyl-4-piperidone 
• 91-16-7 1,2-dimethoxybenzene 

Downstream Products

• 87766-67-4 1-<4-(2,3-Dimethoxyphenyl)-1,2,3,4-tetrahydro-1-methyl-pyrid-4-yl>-4-hydroxy-1-butanone 
• 87766-69-6 (1R*,5R*,6S*)-5-(2,3-Dimethoxyphenyl)-2-methyl-6-(3-hydroxypropyl)-7-oxa-2-azabicyclo<3.2.1>octane 

Relevant academic research and scientific papers

Convenient Synthesis of 3-Methyl-2,3,4,4aα,5,6,7,7aα-octahydro-1H-benzofuroisoquinoline

A new synthesis of 3-methyl-2,3,4,4aα,5,6,7,7aα-octahydro-1H-benzofuroisoquinoline (3) has been developed.The synthesis utilizes the acylation of anion 5 with γ-butyrolactone preferentially at the 4-position.Reduction of the resulting keto alcohol