89998-90-3 Usage
Uses
Used in Pharmaceutical Industry:
Uridine, 3'-carbamate is used as a nucleoside analog for the development of potential therapeutic applications, particularly in the treatment of viral infections and cancer. Its modified structure may offer advantages over unmodified uridine, such as improved efficacy or reduced toxicity.
Used in Drug Development:
Uridine, 3'-carbamate is used as a research tool in the field of nucleoside chemistry to explore its altered pharmacokinetic and pharmacodynamic properties. This can lead to the discovery of new drugs with improved therapeutic potential and reduced side effects.
Used in Antiviral Applications:
Uridine, 3'-carbamate may be used as an antiviral agent, where its modified structure could potentially inhibit viral replication or interfere with viral processes, providing a new approach to treating viral infections.
Used in Cancer Therapy:
Uridine, 3'-carbamate may be employed as a component of cancer treatment, where its unique properties could contribute to the development of novel anticancer drugs or enhance the effectiveness of existing therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 89998-90-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,9,9 and 8 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 89998-90:
(7*8)+(6*9)+(5*9)+(4*9)+(3*8)+(2*9)+(1*0)=233
233 % 10 = 3
So 89998-90-3 is a valid CAS Registry Number.
89998-90-3Relevant academic research and scientific papers
Reaction of Uridine and Uridine 5'-Phosphate with Diiminosuccinonitrile and Cyanogen Bromide in Aqueous Solution. Direct Synthesis of the 2,2'-Anhydronucleoside Linkage at 2 deg C
Ferris, J. P.,Yanagawa, H
, p. 2121 - 2125 (2007/10/02)
Reaction of uridine with diiminosuccinonitrile (DISN) at 2 deg C in aqueous solution yields 2,2'-anhydrouridine 3-carbamate (7) (54percent) along with 2,2'-anhydrouridine (8) (10percent), arabinofuranosyluracil (9) (9percent), uridine 2',3'-carbonate (10) (5percent), uridine 2'-carbamate (11) (3percent), and uridine 3'-carbamate (12) (9percent).A similar distribution of reaction products was obtained when BrCN was used in place of DISN.The same reaction products were isolated from the reaction of DISN or BrCN with uridine 5'-phosphate after the phosphate grouping was cleaved from the initial reaction product mixture with alkaline phosphatase.A reaction pathway is proposed in which the imidocarbonate derivative 6 is a common intermediate for product formation.The vicinal 2',3'-hydroxyl groups are essential for reaction as shown by the failure to form stable reaction products with thymidine (17).Adenosine (13), which has vicinal 2',3'-hydroxyl groups, is converted to a mixture of the 2'- and 3'-carbamates (15 and 16) via an imidocarbonate (14) intermediate with DISN or BrCN.The relevance of these studies to chemical evolution is discussed.
