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9000-81-1

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9000-81-1 Usage

Uses

Different sources of media describe the Uses of 9000-81-1 differently. You can refer to the following data:
1. Acetylcholinesterase (AChE) from Sigma has been used in the structure-activity study of phosphoramido acid esters as inhibitors of AChE.
2. Acetylcholinesterase from Electrophorus electricus (electric eel) has been used:in acetylcholinesterase activity assayto study its effects on Xenopus embryonic hippocampal cellsto study the effect of acetylcholine inhibitors on development and plasticity

Definition

Any substance that inhibits or inactivates acetylcholinesterase, thereby preventing the hydrolysis of acetylcholine. Their action leads to an accumulation of endogenous acetylcholine with a resultant hyperactivity of cholinergic neurons, which can prove lethal.

General Description

Predominantly exists as a tetrameric glycoprotein composed of disulfide-linked homodimers with a monomer MW of ~80 kDa.

Hazard

Tremors; convulsions; respiratory failure; death.

Biochem/physiol Actions

Acetylcholinesterase (AChE) is regarded as a biomarker in neurotoxicity. It is a modulator of nitric oxide signal transduction pathway and marker of membrane integrity and aging. The levels of erythrocyte (RBC) AChE are affected on pesticide exposure and in hemolytic anemia. RBC AChE is a marker in Hirschsprung′s disease and inflammation.

Check Digit Verification of cas no

The CAS Registry Mumber 9000-81-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 9,0,0 and 0 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 9000-81:
(6*9)+(5*0)+(4*0)+(3*0)+(2*8)+(1*1)=71
71 % 10 = 1
So 9000-81-1 is a valid CAS Registry Number.

9000-81-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name Acetylcholinesterase from human erythrocytes

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:9000-81-1 SDS

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