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EC 3.1.1.7, also known as Acetylcholinesterase (AChE), is an enzyme that catalyzes the hydrolysis of acetylcholine into choline and acetate. It plays a crucial role in the regulation of neurotransmission in the nervous system by terminating the action of acetylcholine at the synapses.
Used in Pharmaceutical Industry:
EC 3.1.1.7 is used as a target enzyme for the development of acetylcholinesterase inhibitors, which are important in the treatment of various neurological disorders such as Alzheimer's disease and myasthenia gravis.
Used in Research:
EC 3.1.1.7 is used as a research tool in the structure-activity study of phosphoramido acid esters as inhibitors of AChE, helping to understand the molecular mechanisms of enzyme inhibition and guide the design of new drugs.
Used in Neuroscience Research:
EC 3.1.1.7 is used in acetylcholinesterase activity assays to study its effects on Xenopus embryonic hippocampal cells and to investigate the impact of acetylcholine inhibitors on development and plasticity in the nervous system.

9000-81-1

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9000-81-1 Usage

Hazard

Tremors; convulsions; respiratory failure; death.

Biochem/physiol Actions

Acetylcholinesterase (AChE) is regarded as a biomarker in neurotoxicity. It is a modulator of nitric oxide signal transduction pathway and marker of membrane integrity and aging. The levels of erythrocyte (RBC) AChE are affected on pesticide exposure and in hemolytic anemia. RBC AChE is a marker in Hirschsprung′s disease and inflammation.

Check Digit Verification of cas no

The CAS Registry Mumber 9000-81-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 9,0,0 and 0 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 9000-81:
(6*9)+(5*0)+(4*0)+(3*0)+(2*8)+(1*1)=71
71 % 10 = 1
So 9000-81-1 is a valid CAS Registry Number.

9000-81-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name Acetylcholinesterase from human erythrocytes

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:9000-81-1 SDS

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