9000-97-9 Usage
Uses
Converts L-aspartate and alpha-ketoglutarate to oxaloacetate and L-glutamate
Definition
An enzyme that catalyzes reversibly the transfer of an amino group from glutamic acid to oxaloacetic acid, yielding α-ketoglutaric acid and aspartic acid. The codons for aspartate are GAC and GAU.
General Description
Glutamic-Oxalacetic Transaminase is found in all tissues and is predominant in the liver and skeletal muscle. It is a prototype of fold-type I pyridoxal 5′-phosphate (PLP)-enzymes. Glutamic-oxalacetic transaminase is a homodimer containing large and small domains in each subunit.
Biochem/physiol Actions
Glutamic-oxalacetic transaminase or aspartate aminotransferase (AAT) catalyzes the interconversion of L-aspartate and α-ketoglutarate with oxalacetate and L-glutamate. This reversible transaminase reaction is dependent on pyridoxal 5′-phosphate (PLP). Glutamic-oxalacetic transaminase maintains the nitrogen currency for metabolism by generating L-glutamate. Elevated serum levels of glutamic-oxalacetic transaminase are indicated in myocardial infarction, liver diseases, and some renal diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 9000-97-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 9,0,0 and 0 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 9000-97:
(6*9)+(5*0)+(4*0)+(3*0)+(2*9)+(1*7)=79
79 % 10 = 9
So 9000-97-9 is a valid CAS Registry Number.
