90001-34-6 Usage
General Description
4-Bromo-1,5-naphthyridine is a chemical compound with the molecular formula C9H6BrN. It is a heterocyclic aromatic compound that contains both nitrogen and bromine atoms. This chemical is used as a building block in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It is also used in research and development as a starting material for the production of various substances. 4-Bromo-1,5-naphthyridine is known for its potential applications in the field of medicinal chemistry and drug discovery, as well as in the development of new materials with specific properties. However, it is important to handle this chemical with care, as it may pose hazards to human health and the environment if not properly managed.
Check Digit Verification of cas no
The CAS Registry Mumber 90001-34-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,0,0,0 and 1 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 90001-34:
(7*9)+(6*0)+(5*0)+(4*0)+(3*1)+(2*3)+(1*4)=76
76 % 10 = 6
So 90001-34-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H5BrN2/c9-6-3-5-10-7-2-1-4-11-8(6)7/h1-5H
90001-34-6Relevant articles and documents
Zn-, Mg-, and Li-TMP Bases for the Successive Regioselective Metalations of the 1,5-Naphthyridine Scaffold (TMP=2,2,6,6-Tetramethylpiperidyl)
Balkenhohl, Moritz,Greiner, Robert,Makarov, Ilya S.,Heinz, Benjamin,Karaghiosoff, Konstantin,Zipse, Hendrik,Knochel, Paul
, p. 13046 - 13050 (2017/09/06)
A set of successive regioselective metalations and functionalizations of the 1,5-naphthyridine scaffold are described. A combination of Zn-, Mg-, and Li-TMP (TMP=2,2,6,6-tetramethylpiperidyl) bases and the presence or absence of a Lewis acid (BF3?OEt2) allows the introduction of up to three substituents to the 1,5-naphthyridine core. Also, a novel “halogen dance” reaction was discovered upon metalation of an 8-iodo-2,4-trifunctionalized 1,5-naphthyridine allowing a fourth regioselective functionalization. Additionally, reactions leading to key 1,5-naphthyridines for the preparation of OLED materials and a potential antibacterial agent were performed.