90003-84-2Relevant academic research and scientific papers
Pentacoordinate hydrochlorosilanes with lactamomethyl ligand
Pestunovich, Vadim A.,Kirpichenko, Svetlana V.,Lazareva, Natal'ya F.,Albanov, Aleksander I.,Voronkov, Mikhail G.
, p. 2160 - 2167 (2007)
The synthesis and reaction behavior of pentacoordinate hydrochlorosilanes LCH2SiRHCl (L- 2-piperidonyl ligand, R = Me, Ph, Bn) are described. The intramolecular O-Si and N-Si coordination is discussed on the basis of the NMR data. The strength
Kinetic Resolution of Tertiary Propargylic Alcohols by Enantioselective Cu?H-Catalyzed Si?O Coupling
Seliger, Jan,Dong, Xichang,Oestreich, Martin
supporting information, p. 1970 - 1974 (2019/01/29)
A broad range of tertiary propargylic alcohols were kinetically resolved by catalyst-controlled enantioselective silylation. This non-enzymatic kinetic resolution is catalyzed by a Cu?H species and makes use of the commercially available precatalyst MesCu/(R,R)-Ph-BPE and a simple hydrosilane as the resolving reagent. Both alkyl,aryl- as well as dialkyl-substituted propargylic alcohols participate, and especially high selectivity factors are achieved when the alkyne terminus carries a TIPS group, which also enables facile post-functionalization in this position (s up to 207).
