90005-90-6

Basic information

• Product Name: Phenol, 2-ethyl-5-nitro-
• Synonyms: Phenol, 2-ethyl-5-nitro-
• CAS NO: 90005-90-6
• Molecular Formula: C₈H₉NO₃
• Molecular Weight: 167.16
• Mol File: 90005-90-6.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Phenol, 2-ethyl-5-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 2-ethyl-5-nitro-(90005-90-6)
• EPA Substance Registry System: Phenol, 2-ethyl-5-nitro-(90005-90-6)

Safety Data

• Hazardous Substances Data: 90005-90-6(Hazardous Substances Data)

Upstream product

• 20191-74-6 2-ethyl-5-nitroaniline 
• 578-54-1 ortho-ethylaniline 

Downstream Products

• 91134-43-9 <5-Nitro-2-ethyl-phenoxy>-essigsaeure-methylester 
• 90610-19-8 2-ethyl-5-nitro-anisole 
• 91012-54-3 (5-Amino-2-aethyl-phenoxy)-essigsaeure 
• 15118-84-0 <4,5-Dichlor-2-ethyl-phenoxy>-essigsaeure 
• 27581-23-3 <5-Chlor-2-ethylphenoxy>-essigsaeure 
• 90923-02-7 <5-Nitro-2-ethyl-phenoxy>-essigsaeure 
• 100965-09-1 1-(2-benzoyloxy-4-nitro-phenyl)-2-bromo-ethanone 
• 100961-78-2 1-(2-benzoyloxy-4-nitro-phenyl)-ethanone 
• 90564-14-0 1-(2-methoxy-4-nitrophenyl)ethanone 
• 5230-72-8 2-bromo-1-(2-hydroxy-4-nitro-phenyl)-ethanone 
• 1834-91-9 2-hydroxy-4-nitroacetophenone 
• 933045-59-1 2-ethyl-5-(thiazol-2-ylamino)phenol 
• 207923-07-7 5-amino-2-ethyl-phenol 

Relevant articles and documents

COMPOUNDS AND METHODS FOR THE TREATMENT OF VIRUSES AND CANCER

The present invention relates to compounds according to the formula I: Where Ra is H or an optionally OH-substituted C1-C3 alkyl; R1 is OR1, an optionally substituted C4-12 carbocyclic group which may be saturated or unsaturated (including aromatic) or an optionally substituted heterocyclic group; R1 is an optionally substituted C1-C14 hydrocarbyl group or an optionally substituted heterocyclic group;; R2 , R3 and R4 are each independently H, an optionally substituted C1-C4 alkyl group (preferably CH3, CH2CH3 or CF3), halogen (preferably F, Cl, Br), OR, CN, NO2, a C1-C6 thioether, a C1-C6 thioester group, an optionally substituted CO2R group, an optionally substituted COR group or an optionally substituted OCOR group (preferably R4 is H); R is H or an optionally substituted C1-C6 alkyl group; RHET is an optionally substituted heterocyclic group; and pharmaceutically acceptable salts, solvates or polymorphs thereof.

CINNOLINE AND QUINAZOLINE DERIVATES AS PHOSPHODIESTERASE 10 INHIBITORS

The present invention is directed to cinnoline and quinazoline compounds of formula (I) that are PDE10 inhibitors, pharmaceutical compounds containing the same and processes for preparing the same. The invention is also directed to methods of treating diseases mediated by PDE10 enzyme such as obesity, non-insulin dependent diabetes, schizophrenia or bipolar disorder, obsessive-compulsive disorder, and the like.