9001-24-5

Basic information

• Product Name: AC-G, HUMAN
• Synonyms: COAGULATION FACTOR V, HUMAN;COAGULATION FACTOR V, HUMAN PLASMA;HUMAN PLASMA FACTOR V;LABILE FACTOR, HUMAN;FACTOR V;FACTOR V (BOVINE);FACTOR V (HUMAN);AC-GLOBULIN, HUMAN
• CAS NO: 9001-24-5
• Molecular Weight: 0
• EINECS: 232-590-2
• Mol File: 9001-24-5.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: -20°C
• CAS DataBase Reference: AC-G, HUMAN(CAS DataBase Reference)
• NIST Chemistry Reference: AC-G, HUMAN(9001-24-5)
• EPA Substance Registry System: AC-G, HUMAN(9001-24-5)

Safety Data

• WGK Germany: 2
• Hazardous Substances Data: 9001-24-5(Hazardous Substances Data)

Usage

Description

AC-G, HUMAN, also known as Factor V, is a crucial protein involved in the blood coagulation process. It plays a significant role in the conversion of prothrombin to thrombin, which is essential for normal hemostasis. Deficiencies in Factor V can lead to impaired thrombin generation and affect the body's ability to form blood clots.
Source:
Factor V is synthesized in the liver and circulates in the blood plasma.
Production Methods:
Factor V is produced through a complex process involving the synthesis of its precursor protein, Factor V precursor, in the liver. The precursor protein undergoes post-translational modifications, including cleavage by activated Factor X, to become the active Factor V.

Uses

Used in Coagulopathic Bleeding Studies:
AC-G, HUMAN is used as a key component in the study of coagulopathic bleeding, which occurs following injury and is a leading cause of in-hospital deaths. Deficiencies in Factor V can contribute to this condition, and understanding its role in blood coagulation can help in the development of treatments and interventions to manage coagulopathic bleeding.
Used in Blood Clotting Research:
AC-G, HUMAN is used as a subject of research in the field of blood clotting. Its role in the conversion of prothrombin to thrombin and its interaction with other clotting factors provide valuable insights into the mechanisms of hemostasis and the development of clotting disorders.
Used in Pharmaceutical Development:
AC-G, HUMAN is used as a target for the development of pharmaceuticals aimed at treating clotting disorders and managing coagulopathic bleeding. Understanding the function of Factor V and its interactions with other clotting factors can lead to the development of drugs that modulate its activity and improve blood clotting in patients with deficiencies or dysfunctions in this protein.