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Glutaminase is an enzyme that catalyzes the conversion of glutamine to glutamate and ammonia. It plays a crucial role in various biological processes, including the regulation of nitrogen metabolism and the provision of energy and nitrogen for the synthesis of nucleotides, proteins, and other biomolecules.

9001-47-2

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9001-47-2 Usage

Uses

Used in Neurochemistry:
Glutaminase is used as a tool for the determination of glutamine from the cerebral cortex tissue extract, helping researchers to study the role of glutamine in brain function and neurological disorders.
Used in Analytical Chemistry:
Glutaminase is used for immobilization on aminopropylsilylated controlled pore glass (CPG), enabling the determination of glutamine levels in various samples. This application aids in the development of sensitive and specific analytical methods for glutamine measurement.
Used in Cancer Research:
Glutaminase is used in combination with acivicin, an enzyme inhibitor, in in vitro melanoma cells and MCF-7 and OAW-42 cells. This combination is employed for cell proliferation and invasiveness assays, providing valuable insights into the role of glutaminase in cancer cell growth and metastasis.

Biochem/physiol Actions

Glutaminase from Escherichia coli along with acivicin, a glutamine analog regulates proliferation and invasiveness of cancer cells. Bacterial glutaminase is implicated in increasing the life span of cancer patients by lowering the tumor burden.

Check Digit Verification of cas no

The CAS Registry Mumber 9001-47-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 9,0,0 and 1 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 9001-47:
(6*9)+(5*0)+(4*0)+(3*1)+(2*4)+(1*7)=72
72 % 10 = 2
So 9001-47-2 is a valid CAS Registry Number.

9001-47-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name Glutaminase from Escherichia coli

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:9001-47-2 SDS

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