Isocitrate dehydrogenase (IDH) is a crucial enzyme involved in the citric acid cycle, also known as the Krebs cycle or the tricarboxylic acid (TCA) cycle. This enzyme plays a vital role in cellular respiration, as it catalyzes the oxidative decarboxylation of isocitrate to produce alpha-ketoglutarate, carbon dioxide, and NADPH. IDH exists in two forms: IDH1, which is localized in the cytosol and peroxisomes, and IDH2, which is found in the mitochondria. Both forms are essential for energy production and maintaining cellular redox balance. Mutations in the IDH genes have been implicated in various diseases, including cancer, making it a significant target for therapeutic intervention.
The CAS Registry Mumber 9001-58-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 9,0,0 and 1 respectively; the second part has 2 digits, 5 and 8 respectively. Calculate Digit Verification of CAS Registry Number 9001-58: (6*9)+(5*0)+(4*0)+(3*1)+(2*5)+(1*8)=75 75 % 10 = 5 So 9001-58-5 is a valid CAS Registry Number.
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