9001-81-4

Basic information

• Product Name: EC 5.4.2.2
• Synonyms: PGLUM;PHOSPHOGLUCOMUTASE;PHOSPHOGLUCOMUTASE RABBIT MUSCLE;ALPHA-D-GLUCOSE-1,6-BISPHOSPHATASE;ALPHA-D-GLUCOSE-1,6-PHOSPHOMUTASE;ALPHA-D-GLUCOSE 1-PHOSPHATE PHOSPHOTRANSFERASE;EC 5.4.2.2;phosphoglucomutase from rabbit muscle
• CAS NO: 9001-81-4
• Molecular Formula: NULL
• Molecular Weight: 0
• EINECS: 232-634-0
• Product Categories: enzyme
• Mol File: 9001-81-4.mol
• Article Data: 0

Chemical Properties

• Appearance: /ammonium sulfate suspension
• Density: 1.00 g/mL at 20 °C
• Storage Temp.: 2-8°C
• CAS DataBase Reference: EC 5.4.2.2(CAS DataBase Reference)
• NIST Chemistry Reference: EC 5.4.2.2(9001-81-4)
• EPA Substance Registry System: EC 5.4.2.2(9001-81-4)

Safety Data

• Safety Statements: 24/25
• WGK Germany: 1
• Hazardous Substances Data: 9001-81-4(Hazardous Substances Data)

Usage

Chemical Properties

White to light yellow solid

Uses

Different sources of media describe the Uses of 9001-81-4 differently. You can refer to the following data:
1. Phosphoglucomutase exchanges a phosphoryl group with the substrate.
2. Phosphoglucomutase from rabbit muscle may be used in dephosphorylation to investigate the hexose bisphosphate activation of phosphoglucomutase.

General Description

The phosphoglucomutase (PGM) molecule, a single polypeptide chain, is made up of four α/β domains. The domains form a compact heart-shaped structure with a large fissure between the two lobes, and the molecule comprises about 40 secondary structural components. The active enzymatic site of the molecule is located at the bottom of the crevice on the surface of domain I. Rabbit muscle phosphoglucomutase (RB-PGM) is a monomer with unique four-domain architecture.

Biochem/physiol Actions

Phosphoglucomutase (PGM) mainly catalyzes the interconversion of glucose 1-phosphate and glucose 6-phosphate via a glucose 1,6-diphosphate intermediate. Hence it plays a key role in glycolysis and gluconeogenesis.