90012-57-0Relevant academic research and scientific papers
Cyclization of 4,5-diamino pyrazole derivatives and their antibacterial activities
Rizk, Hala F.,Ei-Badawi, Mahmoud A.,Ibrahim, Seham A.,Ei-Borai, Mohamed A.
, p. 1451 - 1459 (2011/10/30)
A convenient synthesis of intermediate 4,5-diamino-3-aryl-1-phenylpyrazoles 4a-4c was reported. The different cyclization reactions were carried out with chalcone, 2-mercaptoacetic acid and p-anisialdehyde, ethyl chloroformate, glyoxal and thiourea to afford different N and S containing heterocycles. The reaction conditions were compared by conventional heating and microwave irradiation. The structures of the cyclization products were determined by analytical and spectroscopic data. All the synthesized compounds were screened for antibacterial activities in vitro. Copyright
Synthesis of a novel series of imidazo[4,5-c]pyrazole derivatives and their evaluation as herbicidal agents
Vicentini, Chiara B.,Manfrini, Maurizio,Mazzanti, Manuela,Scatturin, Angelo,Romagnoli, Carlo,Mares, Donatella
, p. 337 - 342 (2007/10/03)
Ever changing problems in agricultural weed control require periodic introduction of new herbicides. Imidazo[4,5-c]pyrazoles, which were considered of interest as potential herbicides, were synthesized and examined for the pre-emergence, post-emergence, and post-transplant control of weeds in rice against broadleaf and grass weed species. The data obtained suggest that some imidazo[4,5-c]pyrazoles have potential herbicidal activity against a wide range of weeds, with 5-methyl, 5-thiomethyl, and 5-unsubstituted derivatives being the most effective. No herbicidal activity was observed in the 5-methylsulfonylimidazo[4,5-c]pyrazole and imidazo[4,5-c]pyrazolone series.
