900161-50-4

Basic information

• Product Name: (1,5-cyclooctadiene)(pyridine)(tricyclohexylphosphine)iridium(I) tetrakis[3,5-bis(trifluoromethyl)phenyl]borate
• CAS NO: 900161-50-4
• Molecular Weight: 1523.16
• Mol File: 900161-50-4.mol

Chemical Properties

• CAS DataBase Reference: (1,5-cyclooctadiene)(pyridine)(tricyclohexylphosphine)iridium(I) tetrakis[3,5-bis(trifluoromethyl)phenyl]borate(CAS DataBase Reference)
• NIST Chemistry Reference: (1,5-cyclooctadiene)(pyridine)(tricyclohexylphosphine)iridium(I) tetrakis[3,5-bis(trifluoromethyl)phenyl]borate(900161-50-4)
• EPA Substance Registry System: (1,5-cyclooctadiene)(pyridine)(tricyclohexylphosphine)iridium(I) tetrakis[3,5-bis(trifluoromethyl)phenyl]borate(900161-50-4)

Safety Data

• Hazardous Substances Data: 900161-50-4(Hazardous Substances Data)

Upstream product

• 2622-14-2 tricyclohexylphosphine 
• 64536-78-3 Crabtree's catalyst 
• 79060-88-1 sodium tetrakis[(3,5-di-trifluoromethyl)phenyl]borate 

Relevant articles and documents

Iridium(I) N-Heterocyclic Carbene (NHC)/Phosphine Catalysts for Mild and Chemoselective Hydrogenation Processes

The directed chemoselective hydrogenation of olefins has been established by using iridium(I) catalysts, which feature a tuned NHC/phosphine ligand combination. This selective reduction process has been demonstrated in a wide array of solvents, including more environmentally acceptable media, also allowing further refinement of hydrogenation selectivity. The directed, chemoselective hydrogenation of olefins has been established by using iridium(I) catalysts, which feature a tuned NHC/phosphine ligand combination. This selective reduction process has been demonstrated in a wide array of solvents, including more environmentally acceptable media, also allowing further refinement of hydrogenation selectivity.

A common synthetic route to homochiral tetracycles related to pillaromycinone and premithramycinone

Homochiral AB segments for (+)-and (-)-pillaromycinone were prepared in 11 steps from 2-acetylfuran. The synthesis featured an intramolecular Diels-Alder reaction of a 2,5-disubstituted furan and a hydroxyl-directed homogeneous hydrogenation of the tetrasubstituted alkene double bond of two enones. The CD segment was attached by a modified Staunton-Weinreb annulation to produce the desired homochiral tetracycle 21c related to (+)-pillaromycinone. An unusual acetonide migration enabled the synthesis of a tetracyclic model for premithramycinone.