900164-95-6

Basic information

• Product Name: (3R)-3-(Pyrrolidin-1-yl)pyrrolidine
• Synonyms: (3R)-3-(Pyrrolidin-1-yl)pyrrolidine;(R)-1,3'-bipyrrolidine
• CAS NO: 900164-95-6
• Molecular Formula: C8H16N2
• Molecular Weight: 140.226
• Mol File: 900164-95-6.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 215.5 °C at 760 mmHg
• Flash Point: 91.5 °C
• Appearance: /
• Density: 1.014 g/cm³
• Storage Temp.: 2-8°C
• PKA: 10.28±0.20(Predicted)
• CAS DataBase Reference: (3R)-3-(Pyrrolidin-1-yl)pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (3R)-3-(Pyrrolidin-1-yl)pyrrolidine(900164-95-6)
• EPA Substance Registry System: (3R)-3-(Pyrrolidin-1-yl)pyrrolidine(900164-95-6)

Safety Data

• Hazardous Substances Data: 900164-95-6(Hazardous Substances Data)

Usage

General Description

(3R)-3-(Pyrrolidin-1-yl)pyrrolidine is a chemical compound with a molecular formula of C8H15N. It is a chiral compound, meaning it has a non-superimposable mirror image, and the (3R) designation refers to the spatial arrangement of its atoms. This chemical features two pyrrolidine rings connected by a three-carbon chain, and the pyrrolidin-1-yl group indicates that a pyrrolidine ring is attached to a nitrogen atom. (3R)-3-(Pyrrolidin-1-yl)pyrrolidine is often used as a precursor or intermediate in the synthesis of pharmaceuticals and other organic compounds due to its unique structure and reactivity. Additionally, it may have potential applications in the field of organic and medicinal chemistry for the development of new drugs and materials.

Upstream product

• 123-75-1 pyrrolidine 
• 127423-61-4 tert-butyl (3R)-3-methylsulfonyloxypyrrolidine-1-carboxylate 
• 949928-24-9 Boc-pyrrolidino-pyrrolidine 
• 859213-31-3 (S)-1-benzyl-3-(1-pyrrolidinyl)pyrrolidine 
• 900164-96-7 (R)-1'-benzyl-[1,3']bipyrrolidinyl 
• 1215039-65-8 C₁₃H₂₄N₂O₂ 

Downstream Products

• 1215039-65-8 C₁₃H₂₄N₂O₂ 
• 1608129-54-9 [1,3']bipyrrolidinyl-1'-carboxylic acid [5-(4-methoxyphenyl)-2H-pyrazol-3-yl]amide 
• 1355575-47-1 C₁₈H₂₇N₃O 

Relevant articles and documents

Benzimidazole- and indole-substituted 1,3′-bipyrrolidine benzamides as histamine H3 receptor antagonists

Using a focused screen of biogenic amine compounds we identified a novel series of H3R antagonists. A preliminary SAR study led to reduction of MW while increasing binding affinity and potency. Optimization of the physical properties of the ser

NOVEL AZACYCLY-SUBSTITUTED ARYLTHIENOPYRIMIDINONES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS

The invention relates to azacyclyl-substituted arylthienopyrimidinones and their derivatives of formula (I), and their physiologically tolerated salts and physiologically functional derivatives, their preparation, medicaments comprising at least one azacyclyl-substituted arylthienopyrimidinone of the invention or its derivative, and the use of the azacyclyl-substituted aryithienopyrimidinones of the invention and their derivatives as MCH antagonists.

ORGANIC COMPOUNDS

A compound of formula (I) or stereoisomers or pharmaceutically acceptable salts thereof, and their preparation and use as pharmaceuticals (I) wherein R1 R2 R3, R4 and W are as defined herein.