900167-60-4Relevant academic research and scientific papers
Synthesis and activity of tryptophan sulfonamide derivatives as novel non-hydroxamate TNF-α converting enzyme (TACE) inhibitors
Park, Kaapjoo,Gopalsamy, Ariamala,Aplasca, Alexis,Ellingboe, John W.,Xu, Weixin,Zhang, Yuhua,Levin, Jeremy I.
, p. 3857 - 3865 (2009)
A novel series of non-hydroxamate tryptophan sulfonamide derivatives containing a butynyloxy P1′ moiety was identified as inhibitors of TNF-α converting enzyme (TACE). The structure-activity relationship of the series was examined via substitution on the
