900175-01-1

Basic information

• Product Name: 1-(3-BroMo-4-fluorophenyl)ethanol
• Synonyms: 1-(3-BroMo-4-fluorophenyl)ethanol;3-bromo-4-fluoro-2-methylBenzenemethanol;1-(3-Bromo-4-fluorophenyl)
• CAS NO: 900175-01-1
• Molecular Formula: C₈H₈BrFO
• Molecular Weight: 219.0509232
• Mol File: 900175-01-1.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(3-BroMo-4-fluorophenyl)ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-BroMo-4-fluorophenyl)ethanol(900175-01-1)
• EPA Substance Registry System: 1-(3-BroMo-4-fluorophenyl)ethanol(900175-01-1)

Safety Data

• Hazardous Substances Data: 900175-01-1(Hazardous Substances Data)

Usage

General Description

1-(3-BroMo-4-fluorophenyl)ethanol is a synthetic organic compound that belongs to the class of organic compounds known as halobenzenes. This particular chemical is characterized by the presence of a benzene ring in which one or more hydrogen atoms have been replaced by a halogen atom, such as bromine and fluorine in its case. Its chemical formula is C8H7BrFO and its molecular weight is 235.04 g/mol. It appears as an off-white solid in its pure form. 1-(3-BroMo-4-fluorophenyl)ethanol 1-(3-Brom-4-fluorophenyl)ethanol is typically used in the pharmaceutical sector as an intermediate during drug synthesis. Its extreme toxicity or potential environmental impact have not been established but it's always important to handle it with caution.

Upstream product

• 1007-15-4 4-fluoro-3-bromoacetophenone 

Downstream Products

• 891843-33-7 2-bromo-4-ethyl-1-fluorobenzene 

Relevant articles and documents

CYCLOHEXYL GPR40 AGONISTS FOR THE TREATMENT OF TYPE II DIABETES

Disclosed are compounds, compositions and methods for treating of disorders that are affected by the modulation of the GPR40 receptor. Such compounds are represented by Formula (I) as follows: (Formula (I)) wherein R1, R2, R3, A, W, L, Ra, and G are defined herein: and by Formula (II) as follows: (Formula (II)) wherein R1B, WB, LB, and GB are defined herein.

Phenylglycinamide and pyridylglycinamide derivatives useful as anticoagulants

The present invention provides novel phenylglycinamide derivatives of Formula (I) or (IV): or a stereoisomer, tautomer, pharmaceutically acceptable salt, solvate, or prodrug thereof, wherein the variables W, W1, Y, Z, R7, R8, R9, and R11 are as defined herein. These compounds are selective inhibitors of factor VIIa which can be used as medicaments.

PHENYLGLYCINAMIDE DERIVATIVES USEFUL AS ANTICOAGULANTS

The present invention relates generally to phenylglycinamide derivatives that inhibit serine proteases. In particular it is directed to novel phenylglycinamide derivatives, and analogues thereof, which are useful as selective inhibitors of serine protease enzymes of the coagulation cascade; for example thrombin, factor VIIa, factor Xa, factor XIa, factor IXa, and/or plasma kallikrein. In particular, it relates to compounds that are factor VIIa inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of using the same.